Universal influenza vaccine potentially in sightSeptember 13, 2013

The fall ritual of getting an annual influenza shot could join castor oil on the list of bygone remedies within a decade, some scientists say. During research over the last several years at the Advanced Photon Source at Argonne, two teams of scientists closed on what they suspect is the virus’s Achilles’ heel.

Argonne X-rays point way to Nobel Prize, better medicine September 13, 2013

You may not know what research earned the 2012 Nobel Prize in Chemistry. But chances are that it will impact your life or that of someone you know.

An Understanding of Elastin's Properties Springs ForthSeptember 1, 2011

Physiological flexibility comes from the protein elastin, deriving properties from the building-block molecule tropoelastin, which behaves as an ideal elastomer because it loses no energy between stretch and relaxation. Researchers using the U.S.

Brain Iron as an Early Predictor of Alzheimer's DiseaseAugust 1, 2011

New scientific information relevant to Alzheimer's disease, obtained by researchers utilizing the U. S. Department of Energy Office of Science's Advanced Photon Source at Argonne and National Synchrotron Light Source at BNL, points to the use of elevated brain iron content, already observed in late-stage Alzheimer's, as a potential tool for early diagnosis, which would be a major breakthrough in fighting this debilitating neurological illness. More »

Plutonium tricks cells by "pretending" to be ironJuly 8, 2011

Researchers at Argonne National Laboratory and Northwestern University have identified a new biological pathway by which plutonium finds its way into mammalian cells. The researchers learned that, to get into cells, plutonium acts like a "Trojan horse," duping a special membrane protein that is typically responsible for taking up iron.

The molecular mechanics of hearing and deafnessApril 1, 2011

With the help of X-ray light sources at two DOE Office of Science national laboratories, including the Advanced Photon Source at Argonne, researchers have resolved the molecular structure of one key protein important for sound perception and have used this structure, together with molecular dynamics simulations, to understand the protein's mechanics and function in hearing and deafness, while opening the door to a greater understanding of inherited diseases such as progressive myocardial dystrophy.

The workings of a key staph enzyme and how to block itMarch 1, 2011

Researchers using the Department of Energy's Advanced Photon Source at Argonne have determined the structure and mechanism of an enzyme that performs the crucial first step in the formation of cholesterol and is a key virulence factor in staph bacteria, paving the way to the design of molecules that will be much more effective in fighting staph infections and parasitic diseases, and potentially, in cholesterol-lowering. More »

The molecular mechanism of stretch activation in insect muscleDecember 21, 2010

Research carried out at the Advanced Photon Source at Argonne National Laboratory provides an important step toward a full understanding of the physiologically important phenomenon of insect flight muscle stretch activation, which insects use to reduce energy costs in their flight muscles, and which also plays an important role in mammalian cardiac expansion and contraction. More »