Computational biology

Songs in the key of seaSeptember 27, 2012

Soft horns and a tinkling piano form the backbone of “Fifty Degrees North, Four Degrees West,” a jazz number with two interesting twists: it has no composer and no actual musicians. Unless you count bacteria, that is.

New computational method aims to lower risk factors in stem cell transplantationAugust 20, 2012

Researchers have developed a new structure-based methodology to model peptide-HLA binding interactions.

Earth Microbiome Project to catalogue world’s microbesNovember 9, 2011

An initiative called the Earth Microbiome Project, led by Jack Gilbert at Argonne National Laboratory and including scientists all over the world, is tackling the massive task of cataloguing the DNA of all microbes. The knowledge could potentially one day help us understand climate change, increase world food production and even avoid unnecessary surgeries.

Cloud computing and Argonne program help decode German E. coli strainOctober 15, 2011

When a nasty strain of E. coli flooded hospitals in Germany this summer, it struck its victims with life-threatening complications far more often than most strains—and the search for explanation began. Thanks to a unique Argonne-developed computer program and cloud computing testbed, researchers mapped the strain's genes—and came a little closer to understanding the bacterium's secrets.

New knowledgebase will enable energy and environmental innovationsAugust 30, 2011

Last month, the U.S. Department of Energy announced a multi-institutional effort composed of leading scientists from several institutions, including Argonne National Laboratory. The goal of this collaboration is to develop a Systems Biology Knowledgebase (KBase), designed to accelerate our understanding of microbes, microbial communities and plants.

Argonne's MG-RAST metagenome analysis server passes 1-terabase milestoneJuly 1, 2011

MG-RAST, the metagenome analysis server developed and operated by researchers at Argonne National Laboratory and the University of Chicago, has reached a new milestone: 1 terabase (1,012 basepairs) of metagenomic DNA analyzed by the server. Metagenomics refers to the sequencing of DNA from many organisms present in environmental samples. A rapidly growing field of environmental biology, metagenomics allows researchers to gain insights into the roles played by the vast majority of microorganisms in those environments that cannot be grown in laboratory settings.

Argonne scientists awarded supercomputing time to enable scientific breakthroughsNovember 30, 2010

Four researchers at Argonne National Laboratory lead projects that have been awarded a total of 65 million hours of computing time on Argonne’s energy-efficient Blue Gene/P (“Intrepid”) supercomputer. The researchers will conduct advanced simulation and analysis, performing virtual experiments that would be almost impossible and impractical in the natural world.

DOE awards Argonne projects 200 million hours of supercomputer timeJuly 28, 2010

Five researchers at Argonne National Laboratory will lead projects that have been awarded almost 200 million processor-hours of computing time at Argonne’s Leadership Computing Facility.