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Publication

Optimization-Based Simultaneous Alignment and Reconstruction in Multi-Element Tomography

Authors

Di, Zichao; Chen, Si; Gursoy, Doga; Paunesku, Tatjana; Leyffer, Sven; Wild, Stefan; Vogt, Stefan

Abstract

As x-ray microscopy is pushed into the nanoscale with the advent of more bright and coherent x-ray sources, associated improvement in spatial resolution becomes highly vulnerable to geometrical errors and uncertainties during data collection. We address a form of error in tomography experiments, namely, the drift between projections during the tomographic scan. Our proposed method can simultaneously recover the drift, while tomographically reconstructing the specimen based on a joint iterative optimization scheme. This approach utilizes the correlation provided from different view angles and different signals. While generally applicable, we demonstrate our method on x-ray fluorescence tomography from a tissue specimen and compare the reconstruction quality with conventional methods. © 2019 Optical Society of America

Division

MCS

Publication Year

2019

Publication Type

Article

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