Argonne National Laboratory


Argonne’s biosciences staff scientists are involved with a number of important, cross-cutting projects and initiatives across the lab.

The “Small Worlds” project at Argonne is focused on developing a new multi-modal imaging capability for studying complex multi-agent processes in cells and systems of cells across spatial and temporal scales. This experimental platform is comprised of integrated hardware, software, and molecular-scale reporters that will enable the study of systems biology problems that involve many parts and span spatial scales from nanometers to millimeters and temporal scales from subseconds to days.

Another project focus is the Subsurface Biogeochemical Research Program (SBR) Scientific Focus Area (SFA) to identify and understand coupled biotic-abiotic molecular- to core-scale transformations of Fe and S within redox-dynamic environments and understand the effects of Fe and S biogeochemistry on transformation and mobility of major/minor elements and contaminants. 

To accomplish this objective, this project integrates two unique strengths at Argonne — the Advanced Photon Source (APS) for synchrotron-based interrogation of systems and next-generation DNA sequencing and bioinformatics approaches for microbial community and metabolic pathway analysis — with biogeochemistry and microbial ecology.