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Dave Rotsch

Principal Chemist and Deputy Program Manager, Radioisotope Research and Production Manager


David A. Rotsch is Principal Chemist and Deputy Program Manager, Radioisotope Research and Production Program in the Physics Division at Argonne National Laboratory. He is one of the leads that established Argonne as a production site for the U.S. Department of Energy Isotope Program and in developing Argonne’s Isotope Program. Kawtar Hafidi, Jerry Nolen, and Dave Rotsch are the Argonne points of contact for the DOE Isotope Program Office.

Rotsch’s career is focused on advancing the field of radioisotope production, utilizing electron and light ion linear accelerators. He has significant experience in solid-state chemistry, electrochemistry, and separation chemistry, which translates readily to targetry, target recycling and other aspects of isotope production. His current research focuses on the production and processing of high purity radioisotopes for the ultimate purpose as active pharmaceutical ingredients in radiopharmaceuticals. He is leading Argonne’s R&D effort for developing the photonuclear production of 47Sc from titanium targets. He was instrumental in the development of Argonne’s 67Cu production capability and now manages and leads the 67Cu program. Through collaborations with universities and other research institutions, Rotsch is actively investigating nuclear data and demonstrating applications of radioistopes in nuclear medicine.

Rotsch received his BS in chemistry from Eastern Illinois University and his PhD in inorganic chemistry from the University of Iowa, with his thesis work focusing on the development of MRI and X-ray contrast agents. Before coming to Argonne, he obtained his radiochemical training at the University of Missouri Chemistry Department and University of Missouri Research Reactor (MURR).



  • D.A. Rotsch, M.A. Brown, J.A. Nolen, T. Brossard, W.F. Henning, S.D. Chemerisov, R.G. Gromov, J. Greene, Electron linear accelerator production and purification of scandium-47 from titanium dioxide targets. Appl. Radiat. Isot. 2018, 131, 77-82, DOI: 10.1016/j.apradiso.2017.11.007
  • AJ Youker, SD Chemerisov, P Tkac, M Kalensky, TA Heltemes, DA Rotsch, GF Vandegrift, K Alford, JL Bailey, JP Byrnes, RG Gromov, L Hafenrichter, AS Hebden, J Jerden, CD Jonah, JF Krebs, V Makarashvili, B Micklich, KJ Quigley, JF Schnieder, DC Stepinski, Z Sun, KA Wesolowski, Fission Produced 99Mo without a Nuclear Reactor. J. Nuc. Med, 2016, 116.181040, doi: 10.2967/jnumed.116.181040
  • J Chen, FG Kondev, I Ahmad, MP Carpenter, JP Greene, RVF Janssens, S Zhu, D Ehst, V Makarashvili, DA Rotsch, NA Smith, Precise absolute γ-ray and β-decay branching intensities in the decay of 67Cu. Phys. Rev. C. 2015, 92(4), 0443300, DOI: https://​doi​.org/​1​0​.​1​1​0​3​/​P​h​y​s​R​e​v​C​.​9​2​.​0​44330
  • DA Rotsch, T Brossard, S Bihmidine, W Ying, V Gaddam, M Harmata, JD Roberston, M Swyers, SS Jurisson, D Braun, Radiosynthesis of 6’-deoxy-6’[18F]fluorosucrose via automated synthesis and its utility to study in vivo sucrose transport in maize (Zea mays) leaves, PLoS ONE, 10(5), 2015, DOI: https://​doi​.org/​1​0​.​1​3​7​1​/​j​o​u​r​n​a​l​.​p​o​n​e​.​0​1​28989
  • DA Rotsch, KM Reinig, EM Wiess, AB Taylor, CL Barnes, SS Jurisson, Novel Mononuclear and Dinuclear Rhenium (III, IV, and V) Tetradentate N2O2 Schiff Base Complexes, Dalton Transactions, 42(32) 11614-11625, 2013.
  • A Mohammad, JR Olson, DA Rotsch, RD Bemowski, DC Swenson, L Messerle, High- and Mid-Valent Tantalum and Mono (peralkylcyclopentadienyl) tantalum Complexes of the Bicyclic Guadidinate Hexahydropyrimidinate, Organometallics, 32, 2013, 21, 6232-6239, DOI dx​.doi​.org/​1​0​.​1​0​2​1​/​o​m​4​0​0364m


  • M.A. Brown, D.A. Rotsch, J.A. Nolen, (2018) Process for the separation and purification of scandium medical isotopes. US Patent application publication, US 2018/0051359 A1
  • P. Tkac, G.F. Vandegrift, D.A. Rotsch, (2016) Recovery and Purification of Transition Elements. US Patent Application Publication, US 2016/0333442 A1


  • PhD, Inorganic Chemistry, University of Iowa
  • BS, Chemistry, Eastern Illinois University