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Nathan Andrew Seifert

Postdoctoral Appointee

Biography

Research Interests

  • Broadband microwave spectroscopy of molecules and molecular complexes
  • Spectroscopic instrument development, especially with microwave / mm-wave sources
  • Automated and machine learning techniques for assignment of high-resolution molecular spectra
  • Ab initio and density functional theory techniques for the structural and energetic analysis of non-covalent interactions
  • Open-source software for science, broadly defined

Education & Experience

  • B. A. in Chemistry (2010), cum laude, Amherst College (advisor: Gary J. Snyder)
  • Ph.D. in Physical Chemistry (2015), University of Virginia (advisor: Prof. Brooks H. Pâté)
  • Postdoctoral research with Prof. Wolfgang Jäger (2015-2019) at University of Alberta
  • Postdoctoral research with Dr. Kirill Prozument (2019-) at Argonne National Laboratory

Honors and Awards

  • QuestBridge Fellow, full scholarship to Amherst College (2006-2010)
  • Howard Hughes Medical Institute summer science fellow (2007)
  • 4th place, undergraduate, National Academic Quiz Tournaments (NAQT) Intercollegiate Championship, 2007
  • 3rd place, NAQT Sectional Championship (Northeast Region), 2007 
  • 2nd place, ACS Virginia Division Chemistry Olympiad (2nd year chemistry, 2006)
  • 3rd place, ACS Virginia Division Chemistry Olympiad (1st year chemistry, 2005)

Selected Publications

  • Xie, F.; Seifert, N. A.; Jäger, W.; Xu, Y. Conformational panorama and chirality controlled structure-energy relationship in a chiral carboxylic acid dimer”, Angew. Chem. Int. Ed. 202059, 2.
  • Seifert, N. A.; Hazrah, A. S.; Jäger, W. The 1-naphthol dimer and its surprising preference for π−π stacking over hydrogen bonding,” J. Phys. Chem. Lett.201910, 2836. (cover article!)
  • Oswald, S.; Seifert, N. A.; Bohle, F.; Gawirlow, M.; Grimme, S.; Jäger, W.; Xu, Y. The chiral trimer and a metastable chiral dimer of achiral hexafluoroisopropanol: A multi‐messenger study,” Angew. Chem. Int. Ed. 201958, 5080.
  • Seifert, N. A.; Thomas, J.; Jäger, W.; Xu, Y. A direct link from the gas to the condensed phase: a rotational spectroscopic study of 2,2,2-trifluoroethanol trimers,” Angew. Chem. Int. Ed. 201756, 6289
  • Seifert, N. A.; Perez, C.; Neill, J. L.; Pâté, B. H.; Vallejo-Lopez, M.; Lesarri, A.; Cocinero, E. J.; Castaño, F. Chiral recognition and atropisomerism in the sevoflurane dimer,” Phys. Chem. Chem. Phys. 201517, 18282. (cover article!)
  • Perez, C.; Zaleski, D. P.;  Seifert, N. A.; Temelso, B.; Shields, G. C.; Kisiel, Z.; Pâté, B. H. Hydrogen bond cooperativity and the 3D structures of water nonamers and decamers,” Angew. Chem. Int. Ed. 201453, 14368.
  • Seifert, N. A.; Zaleski, D. P.; Perez, C.; Neill, J. L.; Pâté, B. H.; Vallejo-Lopez, M.; Lesarri, A.; Cocinero, E. J.; Castaño, F.; Kleiner, I. Probing the C-H⋅⋅⋅π weak hydrogen bond in anesthetic binding: the sevoflurane-benzene cluster,” Angew. Chem. Int. Ed. 201453, 3210.
  • Perez, C.; Lobsiger, S.; Seifert, N. A.; Zaleski, D. P.; Temelso, B.; Shields, G. C.; Kisiel, Z.; Pâté, B. H. Broadband FT spectroscopy for structure determination: the water heptamer,” Chem. Phys. Lett.2013571, 1
  • Perez, C.; Muckle, M. T.; Zaleski, D. P.; Seifert, N. A.; Temelso, B.; Shields, G. C.; Kisiel, Z.; Pâté, B. H. Structures of cage, prism and book isomers of water hexamer from broadband rotational spectroscopy,” Science2012336, 897.

A complete list of my publications can be found at my Google Scholar profile.