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Oni Basu

Assistant Scientist, Nanoscience

Assistant Scientist (Joint Appointment) & Assistant Professor, Genetic Medicine, University of Chicago


I aim to do research and teach in the multidisciplinary fields of genomics, microfluidics, medicine, and nano- and bio-materials. Combining these various scientific research areas, I will bring new technologies to aid in the diagnosis and treatment of human disease. These are areas where I have trained and sought expertise in through my Ph.D. in soft matter Physics under Dr. Arjun Yodh, followed by my post-doctoral studies in microfluidics in the applied Physics group of Dr. David Weitz and single-cell genomics in the Systems Biology group of Dr. Aviv Regev at the Broad Institute. As a joint appointee at Argonne National Laboratory and University of Chicago, I continue to work in this very exciting interface of science by bringing bio-/nano-materials and device capabilities at Argonne National Laboratory to answer pressing scientific questions in genomics, biology and medicine at the University of Chicago.


  • Ph.D., University of Pennsylvania, Soft Matter Physics
  • Post-doctoral fellow, Broad Institute of MIT and Harvard; Applied Physics, Harvard Engineering and Applied Science

Recent Selected Publications

  • Y. Tao, A. Rotem, H. Zhang, C. B. Chang, A. Basu, A. O. Kolawole, S. A. Koehler, Y. Ren, J. S. Lin, J. M. Pipas, A. B. Feldman, C. E. Wobus and D. A. Weitz, Rapid, targeted and culture-free viral infectivity assay in drop-based microfluidics, Lab on a Chip, DOI: 10.1039/C5LC00556F (2015)
  • E.  Z. Macosko, A. Basu, R. Satija, J. Nemesh, K. Shekhar, M. Goldman, I. Tirosh, A.  R. Bialas, N. Kamitaki, E.  M. Martersteck, J. J. Trombetta, D. A. Weitz, J. R. Sanes, A. K. Shalek, A. Regev and S. A. McCarroll, Highly Parallel Genome-Wide Expression Profiling of Individual Cells Using Nanoliter Droplets, Cell, 161, 1202 (2015)
  • A. Rotem, O. Ram, N. Shoresh, R. A. Sperling, M. Schnall-Levin, H. Zhang, A. Basu, B. E. Bernstein and D. A. Weitz, High-Throughput Single-Cell Labeling (Hi-Scl) for Rna-Seq Using Drop-Based Microfluidics, PLoS ONE10, e0116328 (2015)
  • A. Basu, Y. Xu, T. Still, P. E. Arratia, Z. Zhang, K. N. Nordstrom, J. M. Rieser, J. P. Gollub, D.J. Durian and A. G. Yodh,  Rheology of Soft Colloids Across the Onset of Rigidity: Scaling Behavior, Thermal, and Non-thermal Responses, Soft Matter, 10(17), 3027 (2014)
  • A. Basu, Q. Wen, X. Mao, T. C. Lubensky, P.A. Janmey and A. G. Yodh, Non-affine displacements in flexible polymer networks, Macromolecules, 44,
  • K. N. Nordstrom, E. Verneuil, P. E. Arratia, A. Basu, Z. Zhang, A. G. Yodh, J. P. Gollub and D. J. Durian, Microfluidic rheology of soft colloids above and below jamming, Physical Review Letters, 105, 175701 (2010)