Skip to main content
Technology Commercialization and Partnerships Division

Automatic Cryoloop Alignment for Protein Crystals (IN-06-117)

Argonne licensing opportunity [Available for Express Licensing]

Methods and apparatus for implementing robust and efficient cryoloop auto-centering for crystal location and alignment to the x-ray beam are provided. Image processing techniques are used for recognition of the small protein crystals. The detected crystal location enables crystal positioning in the x-ray beam, and optimization of the x-ray optics such as beam profile and intensity to the size and shape of the protein crystals.