This invention comprises a means to trap a large nylon mesh sandwiched in between two Mylar sheets to trap microfluidic droplets. It is also compatible for trapping batch crystal slurry.
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This invention describes a system for crystallization and data collection of proteins using fixed-target serial crystallography using microfluidic droplet crystallography for the generation of uniform small crystals and a nylon mesh holder for positioning of droplets with crystal (or batch crystal slurries). While the use of nylon has previously been reported in the literature, this invention includes a method and device design for sealing the droplet/slurry loaded mesh between Mylar sheets.