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Thomas S. Brettin

Strategic Program Manager


Thomas Brettin’s current work focuses on the development of projects at the intersection of genomics, artificial intelligence, and leadership scale computing as well as providing ongoing direction on existing bioinformatics at Argonne National Laboratory and the University of Chicago. Active open projects include the NIH funded Bacterial and Viral Bioinformatics Resource Center, the DOE-NIH funded Joint Design of Advanced Computing Solutions for cancer, and the DOE funded exascale computing deep learning application called CANDLE. Thomas also leads projects funded by the defense community. Thomas has been actively working towards bringing genomics based computational approaches to clinical research settings. More recently, initiating and executing projects that align with strategic goals of applying artificial intelligence more broadly to a range of scientific applications.

Over the past two decades, he has led several large genomics research activities that included laboratory and computational projects. These include associating genetic markers to human diseases, using genetic markers for fine resolution identification of microbial pathogens, sequencing pathogen genomes, and comparative analysis of genomic sequences. He also served as a full-time advisor on the Defense Threat Reduction Agency’s Transformational Medical Technologies program involving bioinformatics integration across several sites around the country to identify and characterize viral and bacterial pathogens in detect to treat scenarios.


  • Michigan State University, M.S., 1994
  • Michigan State University, B.S., 1987

Synergistic Activities

  • Program Committee: 2018-2019 International Workshop on Data Management and Analytics for Medicine and Healthcare