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Research Highlight | Argonne National Laboratory

Minimizing complexity in the microbial world

Scientific achievement

In nature, communities of microorganisms that live in all sorts of environments typically work collectively to perform a variety of chemistries. These communities have been refining and improving the way in which they conduct these biochemical transformations for a very long time — they have effectively been performing biochemical research and development” for billions of years. In a new study, Argonne scientists describe a new way to map how communities of organisms are organized at a fundamental level that would enable this biochemical R&D.

Significance and impact

Scientists are keenly interested in customizing and creating communities of microorganisms to perform complex biochemical tasks for societal benefit. These tasks can range from producing high-value chemicals and biofuels to compounds that can be used as drugs or to detoxify pollutants. Together, the emerging areas of synthetic biology and synthetic ecology hold much promise for generating novel solutions to many present-day problems.

Research details

  • Argonne scientists tested how microbial communities from six distinct natural environments could transform individual carbon compounds and how the community itself changes in response to this availability of nutrients.
  • Argonne scientists chose these compounds to broadly represent the thousands of different compounds found naturally in soil and water.
  • The parallelized enrichment strategy that Argonne scientists devised helped to better understand how minimal communities start forming stable interactions and more complex systems over time.

DOI: 10.3389/fmicb.2017.02321

This research was funded by Argonne’s Laboratory Directed Research and Development program.

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