RAPID-446: Autonomous Lab for Biotechnology

 RAPID-446
The RAPID-446 lab enables rapid, high-throughput bioengineering for protein and pathway design.

The RAPID-446: Autonomous Lab for Biotechnology at Argonne National Laboratory enables rapid, high-throughput microbial engineering for protein and pathway design.

What it can do

The capabilities in this lab enable scientists to use artificial intelligence (AI) to drive experimental design, learn from outcomes and automate labs to bridge the power of AI and biology. This lab demonstrates high-throughput design and analysis to guide large-scale innovation in enzyme function, pathways and bioengineered strains. Projects are able to run iteratively, building upon knowledge gained from prior rounds of experiments to recombine components into new designs for evaluation.

SEE THE FACILITY

Featured gallery image 1

Key capabilities

Explore some of the key capabilities that make RAPID-446 unique.

  • Integrated molecular biology and cultivation equipment: Laboratory equipment supporting molecular biology and bacterial cultivation workflows includes an integrated suite of liquid handlers, thermal cyclers, microplate readers and incubators.
  • Extended autonomous operation: Establishment of robust workflows allow autonomous operation of the platform for weeks at a time.
  • Machine learning and AI: Advanced algorithms optimize experiments and identify new patterns in data.
  • Multiple software integration: The lab uses Argonne’s MADSCi software interface to seamlessly operate multiplatform capabilities.