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Computing, Environment and Life Sciences

Applying Computer Vision to Simplify Use of X-Ray Microscopes

Argonne’s 3D X-ray microscope employs computer vision to detect features of interest and capture and visualize data.

We have developed a software-powered, three-dimensional (3D) X-ray microscope with AI-based computer vision algorithms that is as easy to use as a smart phone.

Our software integrates (1) tomographic (CT) reconstruction; (2) neural networks for segmentation or feature detection; and (3) computational geometry algorithms for tasks such as real-time visualization, automated 3D optical-zoom to regions of interest, and smart capture of data during time-resolved 3D imaging experiments.

We demonstrated prototype solutions through 2021 with select Advanced photon Source (APS) users at the 2-BM and 7-BM beamlines. The software (TomoEncoders + TomoScanStream) is now available in plug-n-play for all beamlines using the EPICS interface for instrument control.

More recently, we also demonstrated a similar solution (ROI-finder) for automatically recommending scan locations for X-ray Fluorescence Microscopy at the 9-ID bio-nanoprobe at APS. AI-steer” is a targeted software development effort supported by Argonne’s computational and beamline scientists. The project is employing datasets and access to beamtime through contributions and collaborations from APS users.