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Argonne National Laboratory


Argonne Impacts State by State

Argonne’s collaborations in California and across the United States have led to groundbreaking discoveries and development of new technologies that help meet the nation’s needs for sustainable energy, economic prosperity, and security.

State-by-State Highlights: California

Cerebras and Argonne collaboration leads to fastest AI system

Argonne leverages unprecedented performance from Cerebras CS-1 to solve deep learning computational and science problems. (Image by Argonne National Laboratory)

The world’s fastest AI computer, Cerebras CS-1, is the result of a collaboration between Cerebras Systems, Los Altos, California, which focuses on accelerating artificial intelligence (AI) compute, and the U.S. Department of Energy’s (DOE) Argonne National Laboratory. Argonne was the first national laboratory to deploy the system in 2019 to solve deep learning computational and science problems. Deep learning, a subset of AI, allows computer networks to learn from large amounts of unstructured data.

The CS-1 integrates the Wafer Scale Engine, the fastest AI processor ever built, and enables AI practitioners to answer more questions and explore more ideas in less time. The CS-1 delivers record-breaking performance and scale to AI compute, and its deployment across national laboratories enables the largest supercomputer sites in the world to achieve a hundred- to a thousandfold improvement over existing AI accelerators.

Argonne-led energy storage consortium technology leads to Sepion startup

The Joint Center for Energy Storage Research (JCESR) helps advance promising areas of energy science and engineering from the earliest stages of research to the point of commercialization. (Image by Argonne National Laboratory)

Sepion Technologies, Emeryville, California, was launched using technology developed at the Joint Center for Energy Storage Research (JCESR), one of DOE’s Energy Innovation Hubs. Led by Argonne, JCESR is a partnership of national laboratories, universities and industrial firms with more than 150 researchers. Its mission is to create materials that can be mixed and matched to build a diversity of next-generation batteries to transform transportation and the electric grid the way lithium-ion batteries transformed consumer electronics. JCESR developed a polymer membrane as a component of a novel design for the cells that make up a battery. That membrane gave birth to Sepion.

Since then, Sepion has been commercializing a membrane platform with a suite of products that enhance the performance and economics of lithium batteries and flow batteries. At the heart of the technology are membranes that can be dropped in with existing manufacturing processes to minimize barriers to market entry, the company website said.

Argonne teams with California firms on new drug for melanoma patients

Frequently or severely sunburned skin can cause skin cancer, as seen in this microscope image. Zelboraf®, a drug developed with the help of X-ray light sources, can limit the cancer’s growth. (Image by Convit/Shutterstock)

Researchers from drug discovery company Plexxikon Inc., Berkeley, California, and biotechnology company Genentech, San Francisco, collaborated with Argonne to develop Zelboraf®, which is sold in nearly 50 countries.

While using Argonne’s Advanced Photon Source, researchers determined the structure of a cancer‑causing mutated protein. They searched through hundreds of molecules to determine the structure of the one that could halt the cancer’s spread. The researchers wanted to develop a drug to prevent the enzyme from multiplying. The molecule the scientists selected to use in the drug functions like a lock-and-key mechanism, binding tightly to the mutated protein and blocking signals from it that tell cancer cells to multiply. The U.S. Food and Drug Administration approved Zelboraf® in 2011.